Intense and hyper-competitive, Cristina quickly becomes Meredith's "person" while pursuing a secret relationship with attending cardiothoracic surgeon Preston Burke.

A former model fighting to be taken seriously as a doctor.

Grey's Anatomy – Season 1 Complete: The Surgery That Started it All

The season's primary engine is the "forbidden" romance between Meredith and , who Meredith realizes—on her first day—was her one-night stand from the night before. Key storylines include: 'Grey's Anatomy' Season 1 Episode Guide - LiveAbout

The first season introduces us to five surgical interns at Seattle Grace Hospital, each struggling to survive the lowest rung of the medical hierarchy:

The daughter of legendary surgeon Ellis Grey, Meredith begins her internship while hiding her mother’s battle with Alzheimer's.